The only real weakness on the roulette wheel layout is the fact that all numbers pay the same odds. This is because they are all supposed to be equally likely, but they really aren't. The trick is to figure out a few which are less likely, and evenly bet all the others.
One of the most important tips you could consider when playing roulette as a casino newbie is sticking to the table minimum and focusing on only playing the outside bets. Bet on either black or red for every new spin and you will enjoy a 1:1 payout while covering 18/38 potential combos.